Metastatic Dissemination of a Neuroblastoma
نویسندگان
چکیده
منابع مشابه
REGRESSION OF METASTATIC NEUROBLASTOMA TO GANGLIONEUROMA
The spontaneous regression of neuroblastoma to ganlioneuroma is a rare occurrence. Reviewing the literature, we found no more than 12casesreported.'•2.9.,o.'4.1s We report a case of metastatic neuroblastoma of multifocal skeletal and soft tissue areas with gross deformities which regressed to ganglioneuroma, with good prognosis.
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Neuroblastoma (NB) is considered one of the malignant tumors of the nervous system which originates from primordial neural crest cell and is known as the most common extra-cranial solid tumor in childhood. This tumor which is often intra-abdominal, metastases in various sites including the skull, long bones, liver, bone marrow and lymph nodes, but lung metastasis at initial diagnosis is rare (0...
متن کاملregression of metastatic neuroblastoma to ganglioneuroma
the spontaneous regression of neuroblastoma to ganlioneuroma is a rare occurrence. reviewing the literature, we found no more than 12casesreported.'•2.9.,o.'4.1s we report a case of metastatic neuroblastoma of multifocal skeletal and soft tissue areas with gross deformities which regressed to ganglioneuroma, with good prognosis.
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A neonatal munine neuroblastoma (NB) model has been developed in addition to a munine NB model for metastatic involvement. The S2OY NB cell line used was cloned from the A/Jax murine C1300 NB and was a gift from Dr. M. Nirenberg. Dose-response studies on adult male and female mice given s.c. injections showed no meaningful sex-re batedifferences ineither theappearanceorthegrowth rate of the tum...
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Metastasis is a multistep process that is critically dependent on the interaction of metastasizing tumor cells with cells in the local microenvironment. Within this tumor stroma, vessel-associated pericytes and myofibroblasts share a number of traits, including the upregulated expression of the transmembrane receptor endosialin (CD248). Comparative experiments in wild-type and endosialin-defici...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2017
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2017.05.069